Surface Area

"The greater surface area of nanoparticles for a given mass compared with larger particles of the same chemical composition has been associated with increased inflammogenic toxicity and tumorigenic responses in a a number of studies in experimental animals or cell systems."¹

1. ^ P. Schulte, C. Geraci, R. Zumwalde, M. Hoover, and E. Kuempel, “Occupational Risk Management of Engineered Nanoparticles,” 5 Journal of Occupational and Environment Hygiene 239, 240 (April 2008) (footnotes omitted).