Particle Size and Size Distribution

"The small size of nanoparticles allows them to enter cells and cell organelles to a greater extent than larger particles (depending also on surface chemistry and charge); inside cells, nanoparticles can damage mitochondrial membranes, cause oxidative stress, and increase cell death."¹

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1. P. Schulte, C. Geraci, R. Zumwalde, M. Hoover, and E. Kuempel, “Occupational Risk Management of Engineered Nanoparticles,” 5 Journal of Occupational and Environment Hygiene 239, 240 (April 2008) (footnotes omitted).